GHK-CU PEPTIDES AND ANTI-AGING MEDICINE
Not many anti-aging products have serious clinical data to back them up. That being said, what you are about to read definitely does. GHK-Cu was discovered in 1973 by a scientist by the name of Loren Pickart. It is known to be a naturally occurring copper complex tri-peptide that can be found in human plasma in addition to urine and saliva. This peptide can be released by the body in the event of injury to help aide in the healing process of wounds and is commonly used in anti-aging products.
But what is a tripeptide and why is it important?
A tripeptide in science terminology is a peptide that derives from three amino acids joined by two or three peptide bonds. In terms of GHK-Cu, it is formed from the gylcyl-L-histidyl-L-lysine tripeptide.
A contrasting idea of how vital this peptide is for your skin
Human plasma levels of GHK-Cu is about 200 ug/ml in your 20’s. By the time you are 60 years old, the level drops to around 80 ug/ml.
GHK-Cu peptide in the light of the new gene date is able to:
- Tighten loose skin and reverse thinning of aged skin.
- Repair protective skin barrier proteins.
- Improve skin firmness, elasticity, and clarity.
- Reduce fine lines, depth of wrinkles, and improve the structure of aged skin.
- Smooths rough skin.
- Reduce photo damage, mottled hyperpigmentation, skin spots, and lesions.
- Improve overall skin appearance.
- Stimulate wound healing.
- Protect skin cells from UV radiation.
- Reduce inflammation and free radical damage.
- Increase hair growth and thickness, enlarge hair follicle size.
For the clinical research – click here
But that is not all. The peptide serum also comes in combination with the following three well documented anti aging ingredients: dimethylaminoethanol, hyaluronic acid, and topical estrogen. For men, it comes without the estrogen.
The role of dimethylaminoethanol in cosmetic dermatology
Mitigation of forehead lines and periorbital fine wrinkles, and improving lip shape and fullness and the overall appearance of aging skin. These effects did not regress during a 2-week cessation of application. Beneficial trends (p > 0.05 but </= 0.1) were noted in the appearance of
- Coarse wrinkles
- Under-eye dark circles
- Nasolabial folds
- Sagging neck skin and neck firmness.
The application was found to be well tolerated, with no differences in the incidence of the following between the DMAE and placebo groups
- Erythema
- Peeling
- Dryness
- Itching
- Burning or stinging
For the clinical research – click here
Hyaluronic acid: A key molecule in skin aging
The key molecule involved in skin moisture is hyaluronic acid (HA) that has a unique capacity in retaining water. There are multiple sites for the control of HA synthesis, deposition, cell and protein association, and degradation, reflecting the complexity of HA metabolism. The enzymes that synthesize or catabolize HA and HA receptors responsible for many of the functions of HA are all multigene families with distinct patterns of tissue expression. Understanding the metabolism of HA in the different layers of the skin and the interactions of HA with other skin components will facilitate the ability to modulate skin moisture in a rational manner.
For the clinical research – click here
Treatment of skin aging with topical estrogens.
After treatment for 6 months, elasticity and firmness of the skin had markedly improved and the wrinkle depth and pore sizes had decreased by 61 to 100% in both groups. Furthermore, skin moisture had increased and the measurement of wrinkles using skin profilometry. In addition, it revealed significant, or even highly significant, decreases of wrinkle depth in the estradiol and the estriol groups. On immunohistochemistry, significant increases of Type III collagen labeling were combined with increased numbers of collagen fibers at the end of the treatment period. As to hormone levels, only those of PRL had increased significantly and no systemic hormonal side effects were noted.
For the clinical research – click here
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